The singles quarterfinals of the 2011 Australian Open were played on January 25 and 26.
Men's Singles
- David Ferrer (7), Spain, defeated Rafael Nadal (1), Spain, 6-4, 6-2, 6-3, and advanced to the semifinals.
- Andy Murray (5), UK, defeated Alexandr Dolgopolov (unseeded), Ukraine, 7-5, 6-3, 6-7, 6-3, and advanced to the semifinals.
- Novak Djokovic (3), Serbia, defeated Tomas Berdych (6), Czech Repblic, 6-1, 7-6, 6-1, and advanced to the semifinals.
- Roger Federer (2), Switzerland, defeated Stanislas Wawrinka (19), Switzerland, 6-1, 6-3, 6-3, and advanced to the semifinals.
Women's Singles
- Caroline Wozniacki (1), Denmark, defeated Francesca Schiavone (6), Italy, 3-6, 6-3, 6-3, and advanced to the semifinals.
- Na Li (9), China, defeated Andrea Petkovic (30), Germany, 6-2, 6-4, and advanced to the semifinals.
- Kim Clijsters (3), Belgium, defeated Agnieszka Radwanska (12), Poland, 6-3, 7-6, and advanced to the semifinals.
- Vera Zvonareva (2), Russia, defeated Petra Kvitova (25), Czech Republic), 6-2, 6-4, and advanced to the semifinals.

